Duffy Blood Group
Number of Antigens: 6
Transfusion Reaction: Typically a moderate, delayed transfusion reaction
Anti-Fya and anti-Fyb can cause transfusion reactions that range from mild to severe in nature and may occur immediately after the transfusion (rarely) or more commonly, after a delay. Anti-Fy3 is a cause of mild to moderate, delayed transfusion reactions.
Hemolytic Disease of the Newborn: Anti-Fya causes mild HDN (rarely, severe HDN can occur). Anti-Fyb and anti-Fy3 are uncommon causes of mild HDN.