Blood Group: MNS
Causes HDN: Yes
Critical Titer: 1:16
Anti-N can cause HDN [1, 3]. While anti-N can be naturally occurring, 78% of anti-N antibodies are IgG and can cross the placenta, while only 22% were IgM, so the significance of anti-N should not be dismissed .
1 - https://www.ncbi.nlm.nih.gov/books/NBK2274/
2 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140072/
3 - http://onlinelibrary.wiley.com/doi/10.1111/j.1423-0410.1976.tb02196.x/full