Anti-Jkc (JK3)

Blood Group: Kidd

Common:  Rare in most populations, found in 0.9% Polynesians

Causes HDN: Yes
Critical Titer: 
Anti-Jk3 is made by individuals with the rare JK-null phenotype. This is Jk (a-b-). This single antibody recognizes both Jka and Jkb antigens. Anti-Jk3 can cause HDN in pregnancy and will hemolyse donor blood in a blood transfusion. [1] In two reported cases of anti-Jk3 [2, 3], the infants were treated with phototherapy. No transfusions were necessary.

1 -
2 -
3 -
4 -