Blood Group: Rh

Common: 2% of caucasians, 2% of blacks, and 4% of asians are at risk for developing anti-E

Causes HDN: Yes
Critical Titer: 1:16*

Anti-E typically causes mild HDN, but can cause severe HDN. During pregnancy, anti-E can cause death, so it is important to be monitored [2]. *One study showed that titers weren't accurate for anti-E and suggested serial MCAs [3]. Anti-E is known for rebounding jaundice after birth more so than anemia. In some cases, IVIG [6] and exchange transfusion may be needed [5]. 

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