Blood Group: Rh
Common: 2% of caucasians, 2% of blacks, and 4% of asians are at risk for developing anti-E
Causes HDN: Yes
Critical Titer: 1:16*
Anti-E typically causes mild HDN, but can cause severe HDN. During pregnancy, anti-E can cause death, so it is important to be monitored . *One study showed that titers weren't accurate for anti-E and suggested serial MCAs . Anti-E is known for rebounding jaundice after birth more so than anemia. In some cases, IVIG  and exchange transfusion may be needed .
1 - https://www.ncbi.nlm.nih.gov/books/NBK2269/