Kell Blood Group
Number of Antigens: 25
Transfusion Reaction: Can cause a severe hemolytic transfusion reaction
Anti-K and anti-Ku are capable of causing a severe reaction. A milder reaction is caused by anti-k, anti-Kpa, anti-Kpb, anti-Jsa, and anti-Jsb.
Hemolytic Disease of the Newborn: Can cause severe fetal anemia
Kell isoimmunization is the third most common cause of HDN after Rh and ABO. Anti-Kell causes severe fetal anemia by suppressing fetal RBC synthesis