Anti-Wra

Blood Group: Diego

Common: 

Causes HDN: Yes
Critical Titer: 1:16
Information:

Anti-Wra can cause severe HDN [1]. HDN from anti-Wra has been treated with IVIG, transfusion and phototherapy [4].


Like anti-Dia, anti-Wra has been known to be undetectable on maternal indirect coombs test during pregnancy, yet still cause issues with the infant after birth [2, 3]. Specialized testing may be required.

Articles:

1 - https://www.ncbi.nlm.nih.gov/books/NBK2273/
2 - https://www.ncbi.nlm.nih.gov/pubmed/6463512
3 - https://www.ncbi.nlm.nih.gov/pubmed/22984759
4 - https://www.ncbi.nlm.nih.gov/pubmed/22397791