Anti-N

Blood Group: MNS

Common:

Causes HDN: Yes
Critical Titer: 1:16
Information:
Anti-N can cause HDN [1, 3]. While anti-N can be naturally occurring, 78% of anti-N antibodies are IgG and can cross the placenta, while only 22% were IgM, so the significance of anti-N should not be dismissed [2]. 


Articles:

1 - https://www.ncbi.nlm.nih.gov/books/NBK2274/

2 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140072/

3 - http://onlinelibrary.wiley.com/doi/10.1111/j.1423-0410.1976.tb02196.x/full