Anti-Jkc (JK3)

Blood Group: Kidd

Common:  Rare in most populations, found in 0.9% Polynesians

Causes HDN: Yes
Critical Titer: 
Information:
Anti-Jk3 is made by individuals with the rare JK-null phenotype. This is Jk (a-b-). This single antibody recognizes both Jka and Jkb antigens. Anti-Jk3 can cause HDN in pregnancy and will hemolyse donor blood in a blood transfusion. [1] In two reported cases of anti-Jk3 [2, 3], the infants were treated with phototherapy. No transfusions were necessary.


Articles:
1 -  https://www.ncbi.nlm.nih.gov/books/NBK2272/
2 -  http://onlinelibrary.wiley.com/doi/10.1046/j.1537-2995.1980.20280169959.x/abstract
3 - http://onlinelibrary.wiley.com/doi/10.1111/j.1423-0410.1982.tb00033.x/full
4 - http://indianpediatrics.net/dec1998/dec-1251-1253.htm