Anti-E

Blood Group: Rh

Common: 2% of caucasians, 2% of blacks, and 4% of asians are at risk for developing anti-E

Causes HDN: Yes
Critical Titer: 1:16*
Information:

Anti-E typically causes mild HDN, but can cause severe HDN. During pregnancy, anti-E can cause death, so it is important to be monitored [2]. *One study showed that titers weren't accurate for anti-E and suggested serial MCAs [3]. Anti-E is known for rebounding jaundice after birth more so than anemia. In some cases, IVIG [6] and exchange transfusion may be needed [5]. 


Articles:
1 - https://www.ncbi.nlm.nih.gov/books/NBK2269/
2 - https://www.ncbi.nlm.nih.gov/pubmed/15625137
3 - http://onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2000.tb11662.x/full
4 - https://www.ncbi.nlm.nih.gov/pubmed/9347637
5 - http://europepmc.org/abstract/med/12405439
6 - http://www.tandfonline.com/doi/abs/10.3109/14767050903544751