Blood Group: Rh
Common: 32% of caucasians, 73% of blacks and 7% of asians are at risk for developing anti-c
Causes HDN: Yes
Critical Titer: 1:16
Anti-c can cause severe HDN . One of the most important things to note is that with anti-c the direct coombs test done on baby can come back negative, but baby still be severely (or fatally) affected . Infants affected by anti-c may need no intervention, or they may require phototherapy, IVIG, exchange transfusion, or RBC transfusion.
1 - https://www.ncbi.nlm.nih.gov/books/NBK2269/