Blood Group: Rh
Common: 20% of caucasians, 4% of blacks, and 53% of asians are at risk for developing anti-C
Causes HDN: Yes
Critical Titer: 1:16
Anti-C can cause severe HDN . One of the most important things to note is that with anti-C the direct coombs test done on baby can come back negative, but baby still be severely (or fatally) affected . Because anti-C can require IUTs and cause fetal death, monitoring for anti-C needs to proceed as aggressively as with anti-D . IVIG can be used to treat jaundice due to anti-C .
1 - https://www.ncbi.nlm.nih.gov/books/NBK2269/